It is frightening to learn that most of our traditional medical doctors prescribe Provera, a synthetic progesterone even though it has never been approved for treatment of Menopause by the F.D.A.

In Great Britain, natural progesterone treatment for PMS is so widely accepted that in three different murder trials, women were sentenced to take "natural progesterone". Their defense was that they committed violent crimes because they were pre-menstrual!

Progesterone is the key factor in the biosynthesis of other hormones, and it also has many other important functions in the body.

Hormones convey their messages only where receptors are available. The range of progesterone receptors throughout the body illustrates the multiple roles of progesterone.

Progesterone has been used in studies to prevent endometrial hyperplasia, to stop menstruation, stop ovulation, and it has been approved by the F.D.A. for treating amenorrhea. However, when progesterone is taken orally, it is absorbed and transported to the liver where 80 to 90 percent is converted to metabolites which are meant to be excreted by the body.

This is why doctors using oral progesterone have to prescribe doses as high as 200 mg per day to get results. Since some of these metabolites do enter the general circulation and have undesirable side effects, oral dosing should be avoided.

Transdermal creams are the perfect and most effective way to get the proper physiological dose of progesterone. 

Stress is almost always involved in PMS. Stress increases levels of cortisol, which block progesterone from its receptor sites. Therefore, normal progesterone levels do not mean that supplemental progesterone is not needed. When a woman discovers she has a handle on controlling her PMS, it will help her manage her stress.

The primary symptoms of true estrogen dominance are hot flashes, night sweats and vaginal dryness. Normally one would associate these symptoms with estrogen deficiency, but we have found that estrogen dominance causes desensitizing of the receptor site and the same effect of estrogen deficiency. By introducing progesterone, this allows the sensitizing of the receptor site and invites the estrogen to attach and thus relieves the symptoms of the hot flashes, night sweats and vaginal dryness.

In a study done by Dr. John Lee and published in the Medical Journal, Lancet, 63 women were given a natural progesterone cream. The women's ages ranged from the 30's to the 80's. The average gain in bone density measured 15%, over three years, with virtual elimination of osteoporotic fractures. Many women with the lowest density scores improved as much as 40%.

Dr. Lee later expanded the study to 100 women and found that only 3 did not respond to the progesterone cream. Of those 3, one was so depressed over the death of her husband that she had quit eating and exercising. The second woman needed hydrochloric acid supplementation and then gained bone density. The third woman was secretly taking excess thyroid medication, which was corrected and she too gained density.

Excessive estrogen causes swelling in the brain. Enlarged blood vessels in the brain cause most migraine headaches. Estrogen can also deplete magnesium levels, which make arteries more susceptible to spasm, a common cause of other types of headaches. For most women, it is that simple. If they have pre-menstrual headaches, progesterone cream and magnesium will usually cure them within three menstrual cycles.

This is a general overview of the studies on the use of progesterone cream. I have a list of suggested books for more in-depth material listed in Library.