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APPLYING VITAMINS TO SKIN SLOWS WRINKLES, STUDY SAYS

By Irwin Arnoff

PARIS, April 23,1998 (Reuters)

Applying antioxidant vitamins directly to the skin can slow the formation of new wrinkles and erase, to some extent, existing wrinkles and lines, according to a study made public on Thursday.

The study by a nonprofit independent group of French scientists found that applying vitamins C, E and beta-carotene to the skin may significantly reduce the long-term damage caused by ultraviolet radiation, a key component of sunlight.

It may also actually partially reverse damage already done, the scientists said. Exposure to the ultraviolet radiation in sunlight is a key cause of skin "aging."

"We have found that topical antioxidants can benefit the skin significantly and play a protective role," said Dr. Serge Hereberg, the study's coordinator, in a statement. "Our final results determined that regular application of antioxidant vitamins to the skin not only inhibits ultraviolet induced damage... but may also facilitate the repair of existing damage -- the result of which is loss of elasticity which could lead to wrinkling and premature skin aging," he said.

The research group’s work is supported by grants from private firms in various industries. The findings are due to be presented to international dermatology meetings next month, the spokesman told Reuters.

The study, part of a larger eight-year study of nutrition and health in Europe, looked at 160 French women over an 18-month period. Researchers divided the women into four groups. One took the vitamins in the form of pills; a second rubbed the vitamins directly on the skin. The remaining two groups either ingested or applied placebos-harmless compounds containing no vitamins-solely for comparison purposes.

The most profound results clearly showed a marked improvement in the condition of the skin. They found "..a 23% reduction in the formation of new lines and an 8% reduction in existing lines and wrinkles.

Much is already known about the ability of antioxidant vitamins to protect against damaging effects of free radicals, a highly reactive type of oxygen atom that occurs naturally in the body and can harm tissues, constrict blood vessels and stimulate cancer growth. The researchers said their study was the first to focus on the vitamins' effect when applied rather than ingested. The larger study, known as the Supplemental Vitamin & Mineral Antioxidant Trial, or SUM MAX began in 1993 and involves some 15,000 subjects. It is the largest trial of its type on nutrition in Europe.

REUTERS COPYRIGHT 1998

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